The ultimate goal of HIV cure research is to allow HIV-infected individuals to be free of disease in the absence of antiretroviral Sandwich Makers therapy.We discuss current directions and future opportunities aimed at ACIDOPH DBLE STR GOAT achieving sustained virological remission, and possibly eradication.A multidisciplinary approach to HIV cure
After entry into the host cell, the intracellular parasite Toxoplasma gondii resides within a membrane-bound compartment, the parasitophorous vacuole (PV).The PV defines an intracellular, parasite-specific niche surrounded by host organelles, including the Golgi apparatus.The mechanism by which T.gondii hijacks the host VGA Golgi and subverts its f
PIWI-interacting RNAs (piRNAs) protect the germ line by targeting transposable elements (TEs) through the base-pair complementarity.We do not know how piRNAs co-evolve with TEs in chickens.Here we reported that all active TEs in the chicken germ line are targeted by piRNAs, and as TEs lose their activity, the corresponding piRNAs erode away.We obse